When this very powerful drug is used to treat Multiple Sclerosis, Mitoxantrone is another chemotherapy injection not unlike those used to treat lymphomas and leukemia.  But it is because of its powerful immune suppression activity that it is being tried in MS patients.  And there has been success.  This is most promising for patients with the most aggressive MS types like secondary progressive MS.  Mitoxantrone has shown a 66 percent reduction of relapses in one study group of this drug.  Multiple Sclerosis Mitoxantrone therapy is often a last resort for these patients, as little else slows progression or reduces relapses.

Another study compared giving patients with primary-progressive multiple sclerosis Mitoxantrone combined with steroids compared to patients given steroids only.  After half a year, 90% of the group with Mitoxantrone combined with steroids showed no new MRI lesions compared to 31% of the group on steroids only.  That is significant, considering …